What Makes Prodovite® So Unique?
Absorption is NOT the only important factor when considering a supplement. 'Absorption' is a loosely and widely used 'buzz word' that is difficult to prove, which is why it is so easily and widely used, and therefore almost meaningless. Moreover, we could make cardboard more absorbable, but that wouldn't make it provide valuable health benefits to the body. The most important first step to making a great 'Multinutrient' product is selecting the best ingredients. The second step is then ensuring maximum absorption and utilization. Premium quality ingredients that get absorbed and utilized result in superior product benefits and the best value to health. So, ingredient selection is still the most important first step towards making a great product.
Prodovite® is a proprietary VMP35 Multinutrient complex made with premium quality Vitamins, Minerals, and Proprietary Phytonutrients encapsulated in our proprietary SK713 SLP Prodosome® technology. The forms of the nutrients and how they are delivered into the tissues (achieving maximum 'absorption') are crucial to achieving beneficial effects. The Prodosome® technology encapsulates the ingredients in many layers of 'body friendly vehicles' (known as 'capsules', 'envelopes', or 'spheres') to rapidly and sustainably transport nutrients across the membranes of the GI tract (mouth to intestines) and into the blood where they are then transported to target tissues in the body. The evidence indicates that this process facilitates a 'mechanically-induced' bonding of methyl groups abundant in the phospholipids to a number of nutrient ingredients including folic acid and vitamin B12, in the same manner as would occur in a cellular environment. This methyl-bonding ensures that the folic acid and vitamin B12 (for example) are metabolized and available to the cells as much as needed (up to the potency in the product) and at the rate needed without any adverse effects. Overmethylation is not a concern.
In addition to the USP vitamins, Prodovite® contains valuable minerals. Macro minerals (minerals needed by the body in larger quantities) are chelated (or 'bonded') to lactate or citrate, 'body friendly' carrier molecules (called 'ligands') that are more easily metabolized and used by the body.* However, both Macro- and Micro-minerals (minerals needed at much lower levels) are encapsulated in the Prodosome® spheres, which rapidly deliver them through the digestive membranes into the blood stream for consistent dispersal into the body. Normally, minerals are very difficult to liposome as they fall out of the liposomal structure, unlike with Prodosomes.
Prodovite® contains Phytosil™∗, a proprietary AFG110 Phytonutrient blend of herbal and other botanical extracts to enhance health and wellness.∗ The botanical extracts in the Phytosil AFG110 Blend are a 1:1 potency strength. That means we use 1 part herb to just 1 part water for the extraction process. This is an almost non-existent practice in the industry and gives us an incredibly powerful product. This extract ratio is an important contributor to beneficial effects of Prodovite, adding another feature that contributes to making Prodovite® a unique supplement without equal.
The Ingredients in Phytosil™:
Astragalus (Root) Extract:
Astragalus is an 'adaptogen', meaning that it has a normalizing effect and improves the ability of an organism to adapt to environmental factors. Adaptogens interact with 'stress response mediators' involved in the regulation of homeostasis (maintain metabolic balance [or equilibrium]) for energy metabolism, the neuroendocrine system, and the immune system. As such, Astragalus is thought to help protect the body against various stresses, including physical, mental, and/or emotional stress, and promote better immune competence.*
Fo Ti (Root) Extract:
Fo Ti is believed to possess anti-aging/longevity promoting benefits. Research suggests that Fo Ti contains an alkaloid with rejuvenating effects on the nerves, brain cells and endocrine glands. It supports and promotes competent adrenal function and helps to detoxify the body. It is also reported to boost the immune function and increase sexual vigor. It is used in Traditional Chinese Medicine as a liver and kidney tonic; a blood and vital essence toner; and to fortify muscles, tendons and bones.*
Decaf Green Tea (Leaf) Extract [GTE]:
Green tea has powerful antioxidant properties owing to its potent content of polyphenols, especially EGCG. These polyphenols are beneficial bioflavonoids that help increase the strength of the body's connective tissues. This helps to reduce tissue fragility, providing increased protection against the initiation of inflammatory events.* GTE is reported to possess about 20 times more antioxidant power than vitamin C. The decaf form that we use removes the stimulating effects of caffeine.
Chamomile (Flower) Extract:
It is used to improve muscle tone and reduce the potential for spasms. As it contains bioflavonoids, it also improves connective tissue strength, reducing the need to initiate inflammatory events, especially those related to the digestive system; supports a calming and stress relieving effect; and supports restful restorative sleep.*
Citrus Bioflavonoids (from Rose Hips) [CBF]:
Rose hips are a potent natural source of CBFs. Aside from their roles as color pigments in plants, CBFs are best known as tissue builders and antioxidants. CBFs were originally called Vitamin P, supposedly because they improved membrane health and 'permeability'. CBFs help reduce the need to initiate inflammatory events following tissue insult because they strengthen connective tissues. They also appear to reduce the fragility and susceptibility of connective tissue to injury from insulting airborne (inhaled), topical contact, and orally ingested allergens.*
Eleuthero (Root) Extract:
Being safer than caffeine, Eleuthero root extract helps reduce fatigue and enhance endurance, while also supporting calming effects. In addition, it supports energy and stamina, and strengthens the immune system. It is also reported to enhance focus and support liver function.*
Hawthorn Berry Extract:
While not being renowned for this feature, Hawthorn berry is a beneficial source of flavonoids, especially OPCs. Its active ingredients include tannins, flavonoids (such as vitexin, rutin, quercetin, and hyperoside), oligomeric proanthocyanidins (OPCs, such as epicatechin, procyanidin, and particularly procyanidin B-2), flavone-C, triterpene acids (such as ursolic acid, oleanolic acid, and crataegolic acid), and phenolic acids (such as caffeic acid, chlorogenic acid, and related phenolcarboxylic acids). Hawthorne berry supports digestion and cardiovascular function. It helps to improve fatigue; normal heart beat rhythms; exercise performance, tolerance, and breathing; and the strength with which the heart ejects blood into the arteries.*
Gotu Kola (Whole Herb):
Not to be confused with the stimulant Kola nut, in both Traditional Chinese Medicine and Traditional Indian Medicine (Ayurvedic Medicine), Gotu kola is one of the chief herbs for revitalizing the nerves and brain cells. The plant has been referred to as "food for the brain". This oriental herb has been shown to promote tranquility, stress relief, as well as improve mental functions such as focus, concentration and memory. It is believed to fortify the immune system, both cleansing and feeding it, and to strengthen the adrenals. The herb's calming properties help support restful sleep and calming one for yoga and meditative practices. It is commonly used to rebuild energy reserves, improve memory, and reduce fatigue, both mental and physical.∗ Gotu kola contains valuable glycosides and is a source of Vitamin K, magnesium, calcium and sodium.
Ginger Root Extract:
Ginger helps to reduce the need to initiate inflammatory events by strengthening connective tissues, reducing fragility and susceptibility. It is ideal for boosting circulation, supporting blood pressure already within the normal range, and maintaining the proper thickness (viscosity) and fluidity of the blood. Ginger also helps support immune function. Ginger root is a medicinal herb used primarily to promote digestive comfort and reduce various types of discomfort after eating. It also supports controlled and voluntary muscle strength and stability.*
Elderberry (Berry) Extract:
Elderberries are a rich source of natural phytochemicals called flavonoids, which, when introduced into the body in foods, are called 'bioflavonoids'. Flavonoids are also known as Vitamin P for 'permeability factor'. That means they promote the strength, integrity, and permeability of all connective tissues, particularly the cell membranes. By strengthening tissues, flavonoids reduce tissue fragility and susceptibility to damage from various types of insults, including antigens/allergens and trauma. As such, they reduce the need to initiate inflammatory events, maintaining cellular health. Elderberry extract helps boost immune function, reducing the need for water retention and congestion. The flavonoids in Elderberry extract also provide antioxidant benefits and help support the body's fight against viruses. Elderberry also helps support respiratory health. Laboratory studies have shown that elderberry helps maintain the healthy structure and function of the sinus membranes and reduces excessive sinus mucus secretion.*
Many months of exhaustive research resulted in the formulation of Lignaloe™, a very special Proprietary GN14 Phytonutrient blend consisting of:
BiAloe®: Aloe vera has been renowned for centuries as a healing plant.∗ The leaf of the Aloe vera is purported to be filled with a gel containing at least 75 nutrients, 20 minerals, 12 vitamins, 18 amino acids, an array of nutritional sugars, and 200 active enzymes. The super-beneficial active ingredient in Aloe vera is acemannan. However, the natural chemical constituents of Aloe vera can be categorized in the following main areas: Amino acids, anthraquinones (mostly in the leaf itself), enzymes, lignins, minerals, mono- and polysaccharides, salicylic acid, saponins, sterols, and vitamins; it is pretty great stuff! This feature, by the way, is why the unique water extraction process is so very important to preserve and protect the maximum synergistic benefits all the natural components in the leaf gel.
BiAloe is a very special DSR0114 Water-Extracted Freeze Dried Certified Organic Aloe Vera Gel Powder. To achieve the best extract, BiAloe starts with unique (Organic) planting, harvesting, and proprietary processing methods. This results in an Aloe vera powder that is up to 10 times more potent than any commercially available Aloe vera. BiAloe® has the highest total Acemannan, the highest immunomodulatory Acemannan and the highest bio-available Acemannan. While it is one of the most expensive Aloes made, it is the most cost effective to use since it is up to 10 times more potent (and more complete) than other Aloe vera products. 87% of the Acemannan in BiAloe is from 5 Kda to 400 Kda (kilodaltons), which is the Immunomodulatory range. Scientific evidence indicates this range is ideal for Acemannan to be more bioavailable and bioactive. Other aloe products contain mostly high molecular weight Acemannan, and/or do not have the complete range of Acemannans, which are very important to the efficacy of the Aloe.
In keeping with our Quality Control standards, Victory Nutrition International (VNI) chose Lorand Labs as the Aloe supplier because it is the only company that routinely tests for Acemannan (Poly-Acetyl-Mannose) and reports the results. Some of the other Aloe suppliers feature carbohydrate levels, and others total polysaccharide content. But, precious few define the details of their product's content; most don't know. Our investigation determined that all of this rhetoric is designed to confuse investigators. If everyone talks about their products in different terms it is virtually impossible to compare apples to apples. Acemannan is the most important active ingredient whose beneficial effects are synergistically amplified in the presence of all the other naturally occurring wholly preserved components in BiAloe. Acemannan is a sub-group of Poly-Mannosides, which is a sub-group of Polysaccharides; which is a sub-group of Carbohydrates.
We also reviewed head-to-head comparisons of the different popular aloe products, and confirmed our decision that BiAloe is the best product.
Proligna is a Water-Extracted Freeze Dried LPC108 Pinus sylvestris strobilus (Scotch Pine Cone [SPC]) extract supported by 14 patents. Proligna® is the result of at least 30 peer-reviewed studies demonstrating its effectiveness. Proligna extract was shown to increase the number of immune (Dendritic) cells up to 9 fold in less than 2 weeks. Dendritic cells determine the presence of pathogenic antigens (molecular 'bad guys') and then educate the rest of the Immune system to their presence so they can be destroyed. More precisely, dendritic cells present antigens to macrophages (immune cells known as 'Big Eaters') for destruction. Hence, dendritic cells are called 'Antigen Presenting Cells' [APC]. Antigens are harmful molecules foreign to the body that generally cause a health problem (a type of 'pathogen'). Dendritic Cells have the broadest range of antigen presentation, and are probably the most important APCs. Restoration of dendritic cells helps to bolster immune competence.*
Without dendritic Immune cells, the Immune system cannot tell the difference between friend or foe, and often ends up attacking the host body and not the 'pathogens'. With higher levels of dendritic Immune cells, the Immune system is much more efficient in identifying true pathogens. Dendritic cells enable more effective immune attacks on harmful anaerobes (i.e. yeast, parasites, microbes, viruses, etc.). Proligna is also a rich source of lignans and saccharides. Research indicates that conjoining lignans with polysaccharides increases immune potentiating activities.*
Victory Nutrition International (VNI) has invested in extensive scientific and technical due diligence to qualify ingredient selection. Then, rigorous quality control and analytical testing procedures are performed on every batch to ensure consistent and continued compliance with compositional quality standards.
Many of these ingredients individually have a significant amount of research demonstrating impressive health benefits. Collectively, these ingredients are the subject of Victory Nutrition International (VNI)'s proprietary research.
Prodosomes® are unique phospholipid transport molecules that form 'carrier spheres' around multiple nutrients, then effectively shuttle them across digestive system membranes. By continually shuttling many nutrients into circulation at the same time, these nutrient clusters improve the body's ability to re-create, rebuild, and sustain optimal health at an unparalleled frequency.
This patent-pending encapsulation process is used in the manufacturing of Prodovite®, to create a 'multilamellar clustoidal' encapsulation architecture. Essentially, this means that clusters of ion-impregnated and saturated energetically enhanced phospholipids are packed within a liposome; and clusters of those liposomes are layered within a liposome; up to hundreds of concentric layers. This unique structuring allows for minerals and a range of both fat and water soluble compounds to be held collectively at different levels within the spherical layers. Due to these many layers, specific nutrients are instantly released and others are released later in the digestive process to ensure a longer, sustainable, and more beneficial blood serum level. It is precisely this unique attribute that creates maximum nutrient synergy and benefits.
The Prodosome technology reduces active ingredient particles down to microscopically small uniform sizes. This process is called High-Shear TBJet Compression, which is a type of advanced wet milling that mechanically predigests the ingredients resulting in a product having the same size as that in a healthy digestive system. Encapsulating a particle with a reduced size means absorption can begin in the mouth via a rich supply of blood vessels under the tongue. This initial absorption is felt almost instantly. Essentially, the High-Shear TBJet Compression Particle Processing (mechanical pre-digestion) and Prodosome processing (utilizing the EFIquence technology) create phospholipid nutrient carrier structures that effectively mimic biological membrane and fluid properties, increasing 'bio-compatibility' (i.e. 'body friendliness), and reduce reliance on disintegrating and dissolving nutrients. The sucess of this 'mimicry' is demonstrated by the fact that when a production batch of Prodovite is allowed to stand at room temperature for several hours, the temperature rises to 98.6 degrees farenheit and STOPS. That's body temperature! And, that is a profound demonstration that Prodovite behaves just like body fluids and is a factor that makes it so "body friendly". No other dietary supplement known experiences this reaction. These properties ensure a large amount of nutrients get rapidly and sustainably absorbed, even in a digestive system that's weak or compromised. It truly is unprecedented 'Bio-Energetic Nutrition'.
Furthermore, while the stomach is designed to dissolve material into a form suitable for absorption, it can also damage those same particles. The Prodosome® capsules are formulated in a way that protects the payload from the stomach's acid and physical churning, while still being able to be broken down further in the digestive system. Due to the High-Shear TBJet Compression reducing the particle size, once the protective layer is dissolved, the nutrient dense payload has a greater surface area than would otherwise be present, allowing for greater absorption rate.
Even the Prodosome's® phospholipid layers offer nutritional benefits and perform a wide range of other vitally important cellular functions, including:
- Building blocks of the biological cell membranes
- Transmitter of biological signals across cell membranes
- Efficient storage of energy
- Transporter of fat between the gut and liver in digestion
- Acetylcholine source; the most common neurotransmitter substance
Prodosome® Technology allows for a more efficient absorption.∗ Prodovite® utilizes the Prodosome® Technology for all active ingredients. No other product on the market can make that claim. This ensures an extremely high level of nutrient bio-availability while also ensuring that Prodovite® is a one-of-a-kind supplement.
Prodovite® Supplement Live Blood Cell Imaging
Watch stunning before and after results of what an individual's blood analysis looks like. Prodovite's significantly beneficial effects are distinctly different from the mechanisms of products using highly alkaline buffers to 'force' an alkalyzing effect in the blood. Prodovite's effects are based entirely on nourishing the body's natural ability to regulate its own healthy blood properties. Prodovite's pH is right around 4.0. So, it's NOT the pH of Prodovite® that causes its beneficial effects...it is the comprehensive nourishment; giving the body the nutritional resources it needs to regulate and maintain the ideal pH and other important properties necessary for optimal health. The individual's blood is first sampled, then this individual is given 1 ounce of the Prodovite® Multi-Nutrient. The Microscopist waits 5 minutes, and then takes another blood sample. Wait until you see the difference this product makes. This individual was one of the subjects in the clinical study that was published in the journal of Functional Foods in Health and Disease. VNI does NOT endorse people getting Live Blood Cell Analyses. In states where it is allowed, analytical methods and procedures may vary and interpetation of results may be subject to a wide range of interpretations.
Q Can children take Prodovite?
A Yes, over the age of 12. For younger children, check with your Pediatrician.
Q There are many potent multiple vitamin and mineral supplements on the market. What makes Prodovite® better than some really great-looking multis?
A Prodovite® eliminates the need for 'megadose supplements'. Prodovite® provides more complete absorption of its ingredient payload at a much faster rate AND for a longer period of time than conventional supplements. Moreover, Prodovite® contains some very special ingredients unavailable in any other multi technology. (Also see the answer on the Difference between Prodovite® and Whole Food Supplements and the answer on vitamins and minerals being chemical isolates.)
Q What is the difference between the Prodovite® and whole food supplements?
A This is a well-intentioned question, but is not really feasible to assess. There are too many multiple nutrient products on the market to undertake a comparative analysis. Any comparison would be an 'apples to oranges' comparison since the Prodovite® technology represents a breakthrough in nutritional supplementation...no other technology compares. The comparison is not just about the nutrient content. It is about how the ingredients are prepared, processed, encapsulated in phospholipids, and delivered to the body that is strikingly different.
Moreover, we engage in scientific research to validate the beneficial effects of our supplements. Most other companies don't. The best of them rely on the information supplied by the ingredient suppliers IF they use any evidence-based ingredients to begin with. Most of the others use 'borrowed' science', which in most cases is actually 'stolen'. That is, they use the scientific evidence from research on another company's premium quality version to support sales of their cheaper copy-cat version. Or, they don't say anything and hope the consumer stays ignorant and just buys the cheapest product because of the misleading claim that 'it doesn't really matter since they're all the same anyway.'
While we use scientifically validated, evidence-based and branded ingredients, Victory commissions research on OUR finished products to validate their beneficial effects. There is no need for speculation or theoretical conjecture. Other companies need to do the same type of scientific validation if they want to have this information.
Q Vitamins and minerals in most supplements are chemical isolates created in a lab, and are fundamentally and bio-chemically not nearly as beneficial to the human body as total whole food supplements. Please comment.
A Based solely on the quality and diversity of ingredients, whole food supplements can be very beneficial as they are definitely superior to most conventional non-whole food supplements, that is, just USP vitamin and mineral products. Importantly, Prodovite® is a multivitamin, mineral, and botanical formulation, containing very beneficial botanical extracts (i.e. herbs and phytonutrients). If the nutritional ingredients in Prodovite® were in the same form as those nutrients in all of the other standard non-whole food-based multis, then it would not likely be able to dramatically and rapidly change the properties of the blood, which it does. Moreover, and most importantly, you would NOT want to deliver 'undigested' whole food ingredients so rapidly into the blood. That could have disastrous results, 'freaking out the immune system' from the presence of undigested whole food components in the blood.
Keep in mind that after accidents, the number one cause of emergency room visits in this country is digestive problems. So, relying on food and whole supplements that require digestive processing (disintegration & dissolution) is not the best way to guarantee that the supplement ingredients get into the tissues where they are desperately needed...no matter how great the ingredients are or what the source is. The Prodosome® encapsulated ingredients in Prodovite® promote rapid absorption and utilization.
In addition, minerals are not made in a laboratory. They are sourced from the earth or sea. They are then put into a simulated digestive environment with proteins, amino acids, or other organic acids and allowed to react with and bind to the organic acids, forming a 'chelated mineral', bonding in a similar fashion as exists in food.
Prodovite® rapidly achieves the end result of absorption and bioavailability intended by the digestive process. Delivering the nutritional payload directly to the blood in a 'body friendly' form in such a short time is an extraordinary achievement.
Q Is our vitamin whole food based, and is it equivalent to the dehydrated juice-based products?
A See the answer on the difference between Prodovite and Whole Food Supplements.
Q Why is cyanocobalamin used as the source of vitamin B12 in Prodovite® instead of the active methylcobalamin form?
A We appreciate and agree with the desire to have only the best ingredients in the product. The 'best' ingredients also must be the 'most appropriate' ingredients. Cyanocobalamin is an especially common form in the vitamin B12 family. It is the most famous vitamer of the family, because it is, in chemical terms, the most air and water stable. So, the primary reason for using Cyanocobalamin is that Prodovite® is a liquid and methylcobalamin is a much less stable form of B12 than the 'cyano' form.
In addition, vitamin B12 is very fragile, requiring cofactors for digestion and absorption (i.e. 'Intrinsic Factor') significantly reducing its absorption potential. The Low Shear TBJet Compression of ALL the ingredients, followed by the EFIquence™ Technology Prodosome® process of the now-reduced and uniformly sized ingredient particles, eliminates the need of an extended digestive process. As such, B12 absorption is much higher when it is encapsulated within the Prodosome® sphere.
Q Why is alcohol listed as an ingredient in Prodovite?
A A small amount of USP alcohol is used in the Prodosome® production process. The amount of alcohol remaining in the product is extremely small. Most botanical extracts use alcohol both in the extraction process AND as a carrier to optimize absorption of the botanical, since alcohol absorbs rapidly. The amount of alcohol in Prodovite® is nowhere near enough to pose a problem for anyone with an issue with alcohol, especially if it is diluted in water. In addition, this very small amount of alcohol has a mild preservative effect.
Q Why is ascorbic acid used for the vitamin C and not a whole food C complex?
A Once vitamin C is IN the blood, it is no longer a complex food source but has been reduced to its simple chemical form via digestion. Using ascorbic acid is an appropriate form to deliver vitamin C quickly into the blood stream with the SK713 SLP Prodosome® delivery technology. (See also the answer on the Difference between Prodovite® and Whole Food Supplements.)
Q I take a bisphosphonate drug to build my bone density. Can I take Prodovite® as well?
A It's always good to check with your doctor. In the body, cells are created, have a functional life, and then they die; they actually turn themselves off in a sort of cell-suicide process (called "apoptosis" which leads to necrosis [cell death]). Normally, the body disposes of those dead cells. In the case of bone, bisphosphonate drugs prevent the disposal of those dead bone cells, making the bones denser (with dead bone cells) because they build up. While the bone does get 'thicker' and denser, numerous consequences have been reported with this forced retention of dead bone cells. A number of the other functions of the bones (like making red and white blood cells) can also be impaired, leading to unhealthy outcomes. Importantly, instructions for taking these bisphosphonate drugs include recommendations to supplement with Calcium and vitamin D. These instructions validate the need to continue to invest in building healthy bones and tissues whether you are taking these drugs or not! So, YES, continue to take Prodovite® for your health.
Q Lots of competitors quote the Physicians Desk Reference saying that liquid vitamins are absorbed at a 98% rate verses only about 10-20% of vitamins that are capsules or tablet form. And yet there are articles alleging that that statement is misleading. What is the correct answer?
A A liquid delivery alone is not adequate to produce such a high rate of absorption. If you can't disintegrate a tablet within 30 minutes, chances are very high that you won't be able to properly digest the ingredients in a liquid either. In addition, the contents of the liquid are crucial determinants of how well they will be 'digested.' Prodovite® is NOT 'just' a liquid supplement. It is unique and superior owing to its premium quality ingredients, proprietary production process, and the SK713 SLP Prodosome® encapsulation technology.
Q Why are soy lecithin phospholipids in the Prodovite supplement?
A The Prodosome compound is a proprietary blend of naturally occurring ingredients. One of the constituents is known as Phosphatidyl Choline. This compound is essential to the integrity of all cells! The Phosphatidyl Choline used in Prodosomes is derived from Soy Lecithin, a vegetarian source. 100% of the make-up of the soy derived material used in Prodosomes is comprised of Phosphatides. Of that, approximately 90% is Phosphatidyl Choline. The balance is a mixture of Phosphatidyl Serine, Phosphatidylethanolomine, and Phosphatidic Acid. All of the Phosphatides are necessary and beneficial for health. The common components of soy of which some people may be sensitive to, or want to avoid, are the proteins and isoflavones. The material used in the production of Prodosomes contains no protein, isoflavones, or any other substance from soy. Therefore, there is no level of any substance within the finished Prodosomes which people typically avoid.
Q What are the specks I see sometimes on the inside of the neck of the Prodovite bottle or the specks that appear floating on the top of the bottle?
A The residue on the inside of the bottle neck is spatter from the rapid elimination of oxygen following the introduction of a drop of liquid nitrogen. It is the residue from a sort of 'mini-explosion' of oxygen purging from the liquid nitrogen drop, that expands 11,000 times its volume in a millisecond after going into the Prodovite. It is not mold or other nasty substance. It is just Prodovite 'solids residue' following the purging of oxygen and dehydration. It is perfectly safe. Prodovite is not heat treated at any stage of its production. This technology is the best way to prevent oxidation prior to opening. This is also why the Prodovite must be refrigerated after opening.
Q What is the best type of water to use when mixing Prodovite Concentrate?
A You should always use pH neutral water, either purified, distilled, or spring. The neutral pH is water's natural pH, defined as where the concentration of 'H' [aka 'acid'] and the concentration of 'OH' [aka 'alkaline'] meet at pH 7.0 [the concentration of 'H2O']. This allows the various nutrients held within the Prodosome spheres to mix properly and be held in suspension within the water until it is consumed. Furthermore, neutral pH water allows the Prodosome spheres to react properly within the saliva, stomach, and small intestine. Using neutral water to mix Prodovite Concentrate allows the body's own pH's to dictate the release of the nutrient payload from the spheres. It should be remembered that the Prodosome technology mimics cell membrane and biological fluid properties. In this manner, some of the nutrients will be absorbed through sub lingual (under the tongue) passage, much of the nutrient payload will be protected in the acidic environment of the stomach, and then the balance of the enveloped nutrition will be released and absorbed through passive diffusion in the small intestine. The intact Prodosome spheres will even adhere to the wall of the small intestine for an extended period, owing to the natural occurring "stickiness" of the phospholipid portion of the sphere, thereby creating a sustained release effect.
The Prodovite Concentrate should never be mixed in alkaline water. These high pH waters, which go through processing methods to create the pH's of 9 and above, can negatively affect the structure of the Prodosome sphere, or cause them to open too early. The higher alkalinity of this type of water, resembling the pH of the small intestine, can stimulate the spheres to begin opening and releasing the nutrients within the water in the glass. This defeats the whole purpose of encapsulating the nutrients in the first place.
Also, the high pH water may cause to some degree, a deconstruction of the phospholipid matrix. This could result in a reduction in the integrity of the Prodosome architecture, which of course reduces the efficiency of both delivery and bio-availability of nutrients in Prodovite. Moreover, introducing high pH water will force the body to counteract the high pH in panicked efforts to maintain the ideal pH of a particular tissue compartment. This actually represents a type of 'drug-like' imposition on the tissues of the body to 'force' a more alkaline pH to overcome the unhealthy acidic properties. However, what is actually happening is depicted in the following 'over-simplistic' but accurate illustration. If water with a pH of 9.5 is introduced into the body and exerts an alkalizing effect on the blood, that should have a plasma pH of about 7.4, the body will have to respond to that high alkaline pH 'push' by buffering the 9.5 with a pH of 5.3 (via increased CO2 as one type of buffer) to keep the blood at 7.4. This type of chronic 'yo-yo hi-lo' volatility is very distressful to the body.
Q I take prescription medications. Can I still take VNI products?
A You should always check with your healthcare professional. Unfortunately, most healthcare professionals don't know about VNI products; especially regarding the patent-pending absorption technology. This puts the healthcare professional at a disadvantage. So, ask your healthcare pro to review the published study (in the case of Prodovite). In the case of Brain Reward, go to PubMed and review the 32 published clinical studies on the KB220Z ingredient complex. Also, he/she should watch the product webinars and review the product literature. It would be very informative and not a waste of their time. It would be especially great to have an informed healthcare professional support your use of evidence-based VNI products, and even begin to utilize them in their practice.
Q Why is Xylitol in the Prodovite?
A Xylitol is an all-natural sugar alcohol found in many fruits and vegetables and produced in small amounts by the human body. Xylitol has been researched for over 40 years, resulting in thousands of studies confirming its effectiveness and safety. The xylitol used in Prodovite is derived from birch and is certified non-GMO.
Xylitol has no apparent toxicity for humans and studies have demonstrated that fact even when participants had consumed a monthly average level of 1500 grams. By contrast Prodovite taken once a day for 30 straight days will provide just over 60 grams, or roughly 4% of the level shown as safe for monthly consumption. Also, a small study showed a side effect of loose bowels was only experienced in a fraction of children who were consuming upwards of 65 grams per day. Again, 1 dose of Prodovite only delivers about 2 grams.
Xylitol is largely undigested and so provides very little impact on blood sugar or insulin response. The glycemic index for xylitol is 7, while that of glucose is 100. From a health standpoint, xylitol helps to re-mineralize tooth enamel that helps to prevent cavities. It also inhibits the growth of strep and the ability of Haemophilus influenzae to attach to naso-pharyngeal cells. Xylitol in gum or nasal sprays may also help prevent acute ear infections in children.
While not efficient as a source of immediate energy, xylitol may be helpful for recover from heavy exercise or work since it is converted into glucose 6-phosphate and then glycogen, the storage form of carbohydrates often depleted during strenuous activity.
Therefore, the inclusion of xylitol in Prodovite not only has no negative implications, it provides multiple health benefits.
Q I heard a report that xylitol was shown to be toxic to dogs. Since it is in Prodovite, is this a problem?
A A single adult serving of Prodovite contains about 2 grams of xylitol along with a host of other highly beneficial nutrients and botanicals. The concern about xylitol in dogs is based on a highly promoted 2016 published case study that reported a 10.9 lb. neutered male Chihuahua ingested about 1/2 lb. (that's 224 grams) of granulated xylitol (112 times the amount in Prodovite!). The dog suffered vomiting and developed hypoglycemia within 1-2 hours and elevated liver values, suggesting the development of acute liver failure within 12 hours and coagulopathy less than 24 hours after ingestion. Treatment included maropitant, intravenous dextrose, phytonadione, metronidazole, and fresh frozen plasma. N-acetylcysteine (NAC) and S-adenosyl-L-methionine (SAMe) provided hepatic detoxification and support. The dog survived and liver values returned to normal within 1 month post ingestion. No adverse effects to hepatic function have been identified 2 years after acute xylitol toxicity. [Schmid RD and Hovda LR. Acute Hepatic Failure in a Dog after Xylitol Ingestion. J Med Toxicol. 2016 Jun;12(2):201-5.]
Q I see that Prodovite contains folic acid and cyanocobalamin. I was told that I carry the MTHFR gene and cannot methylate these vitamins. I was even told that taking these forms could be very toxic to me and I should take methylated forms of these vitamins instead. It seems like I would be 'throwing the baby out with the bathwater' by not taking Prodovite. Please comment.
A The evidence indicates that this process [the patent-pending Prodosome technology] facilitates a 'mechanically-induced' bonding of methyl groups abundant in the phospholipids to a number of nutrient ingredients including folic acid and vitamin B12 (i.e. 'cyanocobalamin'), in the same manner as would occur in a cellular environment. This methyl-bonding ensures that the folic acid and vitamin B12 (for example) are metabolized and available to the cells as much as needed (up to the potency in the product) and at the rate needed without any adverse effects. Overmethylation (a growing problem) is not a concern. Importantly, based upon numerous factors providing solid evidence that the folic acid was being methylated during the Prodosoming process and/or in the tissues of the body (from production experiments to clinical feedback), our concerns regarding the inability to methylate folic acid by people carrying a particular allele of the MTHFR gene were alleviated.
However, considering the overwhelming impact of marketing messages by manufacturers and marketers of methyl folate products, this explanation has been ignored to a significant extent, and people carrying a particular MTHFR allele are avoiding Prodovite due to its folic acid content. Consequently, there is a significant population of people missing out on the amazing benefits of Prodovite. So, we decided to use an organic 'food-form' of folate, trademarked "Orgen-FA®", in Prodovite, which still benefits in the same manner from the patent-pending Prodosome process technology.
Prodovite now contains a 100% food-form of Folate derived from lemon peel. Folate is a broad term for a class or group of water soluble B-vitamins also known as B9. On the other hand, the term 'Folic Acid' describes an oxidized synthetic compound utilized in food supplements and in many types of fortification in foods. In the U.S., the term 'Folate' relates to a class of tetrahydrofolate (THF) derivatives that are naturally occurring in foods. Sources include green leafy vegetables, citrus fruits, and legumes.
Natural food based folates (THF) can enter the primary folate metabolic cascade. Importantly, food based THF are metabolized in the mucosa of the small intestine. Conversely, folic acid from synthetic forms initially is reduced and methylated in the liver requiring the enzyme 5-Methylenetetrahydrofolate reductase. A percentage of the population may be deficient in this enzyme and unable to effectively methylate (metabolize) the folic acid. Consequently in this situation, a high intake of folic acid may result in unnatural levels of un-metabolized folic acid entering the systemic circulation.
While this has not been a concern for Prodovite, the presence of folic acid in the Prodovite has stirred controversy and some fear. Hence, we made a decision to replace it with the premium quality Orgen-FA. The terms “folate” and 'folic acid' are often used interchangeably (as in some international markets) but they are not one and the same. Folates are members of the B vitamin family (referring to various tetrahydrofolate derivatives) naturally occurring in foods, mainly leafy green vegetables. Folic Acid does not occur naturally.
Importantly, NO adverse effects have been associated with the consumption of excess folate from food. Concerns regarding safety are limited to synthetic folic acid intake.
It is important to note that food based Folate can dramatically improve cardiac health in large numbers of the population. This indicates that it is being properly metabolized and utilized with no adverse effects. "Folate-rich diets have been associated with decreased risk of CVD, including coronary artery disease, myocardial infarction (heart attack), and stroke. A study that followed 1,980 Finnish men for 10 years found that those who consumed the most dietary folate had a 55% lower risk of an acute coronary event when compared to those who consumed the least dietary folate"
[Voutilainen S, Rissanen TH, Virtanen J, Lakka TA, Salonen JT. Low dietary folate intake is associated with an excess incidence of acute coronary events: The Kuopio Ischemic Heart Disease Risk Factor Study. Circulation. 2001;103(22):2674-2680.]
It is also important to note that the methyl folate used in dietary supplements is a "manufactured" (synthesized) form of the vitamin... not from a food source. Usually the folate is bound to a calcium salt. Moreover, Methylfolate is extremely unstable in liquids. It is interesting to note that food based folates are water soluble and very stable in liquids at room temperatures, which is what is now in Prodovite. So, while there has been NO evidence whatsoever that the folic acid in Prodovite has caused any detrimental effects in people who cannot metabolize folic acid, and that the folic acid is fully metabolized owing to the Prodosome technology, we decided to make the change anyway just to eliminate the concerns over the folic acid factor.
One final note, the food based folate in Prodovite is encapsulated within the Prodosome sphere. This facilitates superior delivery and absorption of the folate. As important, the choline content of the Prodosome is a major dietary source of methyl groups. Therefore, both naturally occurring folate and naturally occurring methyl groups are being absorbed simultaneously with Prodovite. This is a very advantageous, holistic, and safe approach to maintaining healthy folate levels and optimizing the beneficial effects of folate.
∗ These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.